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  • Mingxi Deng, Ying Wang, Lina Zhang, Yang Yang, Shengshuo Huang, Jiguang Wang, Hao Ge, Toyotaka Ishibashi, Yan Yan, Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs, Development 2019 : dev.179754 doi: 10.1242/dev.179754. Highlighted in The people behind the papers interview. doi: 10.1242/dev.184309. Highlighted in Editor’s Choice: scDisc: a single cell look at a premier developmental model. Development 2019 146: e1801

  • Tiantian Ji*, Lina Zhang*, Mingxi Deng, Shengshuo Huang, Ying Wang, Tri Thanh Pham, Andrew Alan Smith, Varun Sridhar, Clemens Cabernard, Jiguang Wang, Yan Yan, Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors. Disease Models & Mechanisms. 2019 Aug 1. pii: dmm.040147. doi: 10.1242/dmm.040147. Highlighted in First Person interview. doi: 10.1242/dmm.041798

  • Mengping Long*, Xulun Sun*, Wenjin Shi, Yanru An, Tsz Chui Sophia Leung, Dongbo Ding, Manjinder S. Cheema, Nicol MacPherson, Christopher J Nelson, Juan Ausio, Yan Yan, and Toyotaka Ishibashi, A novel histone H4 variant regulates rDNA transcription in breast cancer. Nucleic Acids Research, 2019 Jun 20. pii: 5521031. doi: 10.1093/nar/gkz547.

  • An Y, Xue G, Yang S, Deng M, Zhou X, Yu W, Ishibashi T, Zhang L, Yan Y. Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts. Development. 2017 Jun 15;144(12):2153-2164. Highlighted in Editor’s Choice, “A new model for single-cell delamination”.

  • Wong KK, Li W, An Y, Duan Y, Li Z, Kang Y, Yan Y. β-Spectrin regulates the Hippo signaling pathway and modulates the basal actin network. J Biol Chem, 2015 Mar 6; 290(10):6397-407. 

  • Li Y, Wei Z, Yan Y, Wan Q, Du Q, Zhang M. Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc Natl Acad Sci USA. 2014 Dec 9;111(49):17444-9. 

  • Yan Y, Denef N, Tang C, Schupbach T. Drosophila PI4KIIIalpha is required in the follicle cells for oocyte polarization and Hippo signaling. Development. 2011 May;138(9):1697-703. • Highlighted in “Editors’ choice”: VanHook AM, Lipids Influence Hippo Signaling. Sci. Signal. 4, ec110 (2011)

  • Yan Y*, Denef N*, Schupbach T. The vacuolar proton pump, V-ATPase, is required for Notch signaling and endosomal trafficking in Drosophila. Dev Cell. 2009 Sep;17(3):387-402.*These authors contributed equally to this work.

  • Sun Y, Yan Y, Denef N, Schupbach T. Regulation of Somatic Myosin Activity by Protein Phosphatase 1beta Controls Drosophila Oocyte Polarization. Development. 2011 May;138(10):1991-2001. 


  • Sethi N, Yan Y, Quek D, Schupbach T, Kang Y. Rabconnectin-3 is a functional regulator of mammalian Notch signaling. J Biol Chem. 2010 Nov 5;285(45):34757-64.

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